| First Quarter |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | | | Rian Lindell kicks off to the Jac1. Quan Cosby return for 21 yards to Jac22. Tackled by Ron Brooks. | | |
| Jac | 1st&10 | Jac22 | Rashad Jennings rush to the left for 5 yards to the Jac27. Tackled by Nigel Bradham and George Wilson. | | |
| Jac | 2nd&5 | Jac27 | Chad Henne incomplete pass to the right intended for Cecil Shorts defensed by Ron Brooks. | | |
| Jac | 3rd&5 | Jac27 | Chad Henne incomplete pass to the right intended for Jordan Shipley. | | |
| Jac | 4th&5 | Jac27 | Bryan Anger punts for 51 yards to Buf22. Leodis McKelvin return for 12 yards to Buf34. Tackled by Montell Owens. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | 1st&10 | Buf34 | C.J. Spiller rush to the right for 2 yards to the Buf36. Tackled by Paul Posluszny and Tyson Alualu. | | |
| Buf | 2nd&8 | Buf36 | Ryan Fitzpatrick incomplete pass to the left intended for Stevie Johnson. | | |
| Buf | 3rd&8 | Buf36 | Ryan Fitzpatrick rush to the left for 11 yards to the Buf47. Tackled by Jason Babin. | | |
| Buf | 1st&10 | Buf47 | C.J. Spiller rush to the right for 9 yards to the Jac44. Tackled by Mike Harris and Paul Posluszny. | | |
| Buf | 2nd&1 | Jac44 | C.J. Spiller rush to the right for 2 yards to the Jac42. Tackled by Aaron Ross and Tyson Alualu. | | |
| Buf | 1st&10 | Jac42 | Penalty: Holding on Buffalo (Chris Hairston) -10 yards. | | |
| Buf | 1st&20 | Buf48 | Ryan Fitzpatrick incomplete pass to the right intended for Stevie Johnson. | | |
| Buf | 2nd&20 | Buf48 | Ryan Fitzpatrick pass to the left to T.J. Graham for 51 yards to the Jac1. Tackled by Kevin Rutland and Chris Prosinski. | | |
| Buf | 1st&1 | Jac1 | Fred Jackson rush up the middle for no gain to the Jac1. Tackled by Chris Prosinski and Tyson Alualu. | | |
| Buf | 2nd&1 | Jac1 | Ryan Fitzpatrick rush up the middle for 1 yard for a TOUCHDOWN. | | |
| Buf | | | Rian Lindell extra point is good. | | |
| Buf | | | Drive Stats: 9 plays, 66 yards, 4min 45sec | 0 | 7 |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | | | Rian Lindell kicks off to the Jac6. Quan Cosby return for 32 yards to Jac38. Tackled by Rian Lindell and Brad Smith. | | |
| Jac | 1st&10 | Jac38 | Chad Henne pass to the right to Marcedes Lewis for 9 yards to the Jac47. | | |
| Jac | 2nd&1 | Jac47 | Rashad Jennings rush up the middle for 1 yard to the Jac48. Tackled by Kyle Williams and Nick Barnett. | | |
| Jac | 1st&10 | Jac48 | Chad Henne incomplete pass to the left intended for Jordan Shipley. | | |
| Jac | 2nd&10 | Jac48 | Rashad Jennings rush up the middle for 4 yards to the Buf48. Tackled by Kelvin Sheppard. | | |
| Jac | 3rd&6 | Buf48 | Chad Henne incomplete pass to the left intended for Justin Blackmon. | | |
| Jac | 4th&6 | Buf48 | Bryan Anger punts for 36 yards to Buf12. No return. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | 1st&10 | Buf12 | Fred Jackson rush up the middle for no gain to the Buf12. Tackled by Dwight Lowery and George Selvie. | | |
| Buf | 2nd&10 | Buf12 | Ryan Fitzpatrick pass to the left to T.J. Graham for 3 yards to the Buf15. Tackled by Jeremy Mincey. | | |
| Buf | 3rd&7 | Buf15 | Ryan Fitzpatrick incomplete pass to the left intended for Scott Chandler. | | |
| Buf | 4th&7 | Buf15 | Shawn Powell punts for 61 yards to Jac24. Quan Cosby return for 6 yards to Jac30. Tackled by Brad Smith. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | 1st&10 | Jac30 | Penalty: Holding on Jacksonville (Brad Meester) -10 yards. | | |
| Jac | 1st&20 | Jac20 | Chad Henne pass to the middle to Marcedes Lewis for 23 yards to the Jac43. Tackled by Bryan Scott. | | |
| Jac | 1st&10 | Jac43 | Rashad Jennings rush to the right for 1 yard to the Jac44. Tackled by Alex Carrington and Shawne Merriman. | | |
| Jac | 2nd&9 | Jac44 | Chad Henne incomplete pass to the left intended for Justin Blackmon. | | |
| Jac | 3rd&9 | Jac44 | Chad Henne pass to Justin Blackmon for 15 yards to the Buf41. Tackled by Stephon Gilmore. | | |
| Jac | 3rd&- | Buf41 | Penalty: Holding on Buffalo (Stephon Gilmore) 5 yards. | | |
| Jac | 1st&10 | Jac49 | Rashad Jennings rush to the right for a loss of 2 yards to the Jac47. Tackled by Alex Carrington and Nick Barnett. | | |
| Jac | 2nd&12 | Jac47 | Chad Henne incomplete pass to the right intended for Cecil Shorts. | | |
| Jac | 3rd&12 | Jac47 | Penalty: Delay of Game on Jacksonville (Chad Henne) -5 yards. | | |
| Jac | 3rd&17 | Jac42 | Chad Henne pass to the right to Cecil Shorts for 18 yards to the Buf40. Tackled by Crezdon Butler. | | |
| Jac | 1st&10 | Buf40 | Rashad Jennings rush up the middle for no gain to the Buf40. Tackled by Nigel Bradham. | | |
| Jac | 2nd&10 | Buf40 | Rashad Jennings rush up the middle for a loss of 1 yard to the Buf41. Tackled by Da'Norris Searcy and Kyle Moore. FUMBLE, recovered by Jac (Marcedes Lewis). | | |
| Jac | 3rd&11 | Buf41 | Chad Henne incomplete pass to the right intended for Kevin Elliott. | | |
| Jac | 4th&11 | Buf41 | Bryan Anger punts for 30 yards to Buf11. No return. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | 1st&10 | Buf11 | C.J. Spiller rush up the middle for 1 yard to the Buf12. Tackled by Terrance Knighton and Andre Branch. | | |
| |
| Second Quarter |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | 2nd&9 | Buf12 | Ryan Fitzpatrick pass to the left to C.J. Spiller for 7 yards to the Buf19. Tackled by Mike Harris. | | |
| Buf | 3rd&2 | Buf19 | C.J. Spiller rush to the right for 3 yards to the Buf22. Tackled by Aaron Ross. | | |
| Buf | 1st&10 | Buf22 | Ryan Fitzpatrick pass intended for Stevie Johnson INTERCEPTED by Paul Posluszny and returned for 5 yards. Tackled by Scott Chandler. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | 1st&10 | Buf32 | Rashad Jennings rush to the right for 12 yards to the Buf20. Tackled by Nick Barnett and Stephon Gilmore. FUMBLE, recovered by Jac (Eben Britton). | | |
| Jac | 1st&10 | Buf17 | Montell Owens rush up the middle for 5 yards to the Buf12. Tackled by Kelvin Sheppard and George Wilson. | | |
| Jac | 2nd&5 | Buf12 | Montell Owens rush to the right for 9 yards to the Buf3. Tackled by George Wilson. Penalty: Unnecessary Roughness on Jacksonville (Cameron Bradfield) -15 yards. | | |
| Jac | 1st&10 | Buf18 | Chad Henne incomplete pass to the left intended for Greg Jones. | | |
| Jac | 2nd&10 | Buf18 | Chad Henne incomplete pass to the right intended for Cecil Shorts defensed by Mario Williams. | | |
| Jac | 3rd&10 | Buf18 | Chad Henne incomplete pass to the right intended for Justin Blackmon defensed by George Wilson. | | |
| Jac | 4th&10 | Buf18 | Josh Scobee 36 yard field goal attempt is GOOD. Holder: Bryan Anger. | | |
| Jac | | | Drive Stats: 7 plays, 14 yards, 1min 53sec | 3 | 7 |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | | | Josh Scobee kicks off to the Buf0. Touchback. | | |
| Buf | 1st&10 | Buf20 | Ryan Fitzpatrick pass to the left to Fred Jackson for 11 yards to the Buf31. Tackled by C.J. Mosley and Dwight Lowery. | | |
| Buf | 1st&10 | Buf31 | Fred Jackson rush to the right for 5 yards to the Buf36. Tackled by Tyson Alualu and Russell Allen. | | |
| Buf | 2nd&5 | Buf36 | Fred Jackson rush to the left for 10 yards to the Buf46. Tackled by Kevin Rutland and Dwight Lowery. | | |
| Buf | 1st&10 | Buf46 | Fred Jackson rush up the middle for 9 yards to the Jac45. Tackled by Jeremy Mincey. | | |
| Buf | 2nd&1 | Jac45 | C.J. Spiller rush up the middle for no gain to the Jac45. Tackled by C.J. Mosley and Tyson Alualu. | | |
| Buf | 3rd&1 | Jac45 | Fred Jackson rush up the middle for 3 yards to the Jac42. Tackled by C.J. Mosley and Paul Posluszny. | | |
| Buf | 1st&10 | Jac42 | Fred Jackson rush up the middle for a loss of 3 yards to the Jac45. Tackled by Jason Babin. | | |
| Buf | 2nd&13 | Jac45 | Ryan Fitzpatrick pass to the left to Stevie Johnson for 5 yards to the Jac40. Tackled by Kevin Rutland. | | |
| Buf | 3rd&8 | Jac40 | Ryan Fitzpatrick rush to the right for 3 yards to the Jac37. Tackled by Aaron Ross and Paul Posluszny. | | |
| Buf | 4th&5 | Jac37 | Buffalo Bills timeout. | | |
| Buf | 4th&5 | Jac37 | Ryan Fitzpatrick incomplete pass to the middle intended for Scott Chandler defensed by Russell Allen. | | |
| Jac | 1st&10 | Jac37 | Penalty: Pass Interference on Buffalo (Ron Brooks) 24 yards. | | |
| Jac | 1st&10 | Buf39 | Chad Henne pass to the left to Cecil Shorts for 24 yards to the Buf15. Tackled by Ron Brooks. | | |
| Jac | 1st&10 | Buf15 | Chad Henne pass to the left to Marcedes Lewis for 12 yards to the Buf3. Tackled by Kyle Williams. | | |
| Jac | 1st&3 | Buf3 | Montell Owens rush up the middle for 2 yards to the Buf1. Tackled by Kelvin Sheppard and Ron Brooks. | | |
| Jac | 2nd&1 | Buf1 | Chad Henne rush to the right for 1 yard for a TOUCHDOWN. | | |
| Jac | | | Josh Scobee extra point is good. | | |
| Jac | | | Drive Stats: 4 plays, 63 yards, 1min 46sec | 10 | 7 |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | | | Josh Scobee kicks off to the Buf4. Marcus Easley return for 55 yards to Jac41. Tackled by Mike Harris. Penalty: Unnecessary Roughness on Jacksonville (Richard Murphy) 15 yards. | | |
| Buf | 1st&10 | Jac26 | Brad Smith rush to the right for 11 yards to the Jac15. Tackled by Dawan Landry. | | |
| Buf | 1st&10 | Jac15 | C.J. Spiller rush to the right for 4 yards to the Jac11. Tackled by C.J. Mosley and Jason Babin. | | |
| Buf | 2nd&6 | Jac11 | C.J. Spiller rush to the left for no gain to the Jac11. Tackled by Dawan Landry. | | |
| Buf | 3rd&6 | Jac11 | Two Minute Warning. | | |
| Buf | 3rd&6 | Jac11 | Ryan Fitzpatrick pass to the middle to Scott Chandler for 11 yards for a TOUCHDOWN. | | |
| Buf | | | Rian Lindell extra point is good. Penalty: Offside on Jacksonville (Andre Branch) 5 yards. | | |
| Buf | | | Drive Stats: 4 plays, 26 yards, 1min 51sec | 10 | 14 |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | | | Rian Lindell kicks off to the Jac0. Touchback. | | |
| Jac | 1st&10 | Jac20 | Chad Henne sacked at Jac14 for a loss of 6 yards by Mario Williams. FUMBLE, recovered by Buf (Mario Williams). Tackled by Cameron Bradfield. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | 1st&10 | Jac14 | Fred Jackson rush up the middle for a loss of 1 yard to the Jac15. Tackled by Jeremy Mincey. | | |
| Buf | 2nd&11 | Jac15 | Ryan Fitzpatrick rush to the right for 4 yards to the Jac11. Tackled by Russell Allen. | | |
| Buf | 3rd&7 | Jac11 | Ryan Fitzpatrick incomplete pass to the left intended for Brad Smith. | | |
| Buf | 4th&7 | Jac11 | Rian Lindell 29 yard field goal attempt is GOOD. Holder: Shawn Powell. | | |
| Buf | | | Drive Stats: 4 plays, 3 yards, 1min 20sec | 10 | 17 |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | | | Rian Lindell kicks off to the Jac3. Quan Cosby return for 9 yards to Jac12. Tackled by Marcus Easley. | | |
| Jac | 1st&10 | Jac12 | Chad Henne rush up the middle for a loss of 1 yard to the Jac11. | | |
| Team | Down | Spot | Play | Jac | Buf |
| |
| Third Quarter |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | | | Josh Scobee kicks off to the Buf1. Brad Smith return for 38 yards to Buf39. Tackled by Mike Harris. | | |
| Buf | 1st&10 | Buf39 | C.J. Spiller rush up the middle for 8 yards to the Buf47. Tackled by Dawan Landry and Paul Posluszny. | | |
| Buf | 2nd&2 | Buf47 | C.J. Spiller rush up the middle for 1 yard to the Buf48. Tackled by Tyson Alualu and Russell Allen. | | |
| Buf | 3rd&1 | Buf48 | C.J. Spiller rush to the left for 3 yards to the Jac49. Tackled by Mike Harris. | | |
| Buf | 1st&10 | Jac49 | Buffalo Bills timeout. | | |
| Buf | 1st&10 | Jac49 | Fred Jackson rush up the middle for 15 yards to the Jac34. Tackled by Russell Allen. | | |
| Buf | 1st&10 | Jac34 | Brad Smith rush to the left for 17 yards to the Jac17. Tackled by Russell Allen. | | |
| Buf | 1st&10 | Jac17 | Ryan Fitzpatrick incomplete pass to the left intended for Fred Jackson defensed by Dawan Landry. | | |
| Buf | 2nd&10 | Jac17 | Penalty: Roughing Passer on Jacksonville (Jason Babin) 9 yards. | | |
| Buf | 1st&8 | Jac8 | Ryan Fitzpatrick incomplete pass to the left intended for Scott Chandler. | | |
| Buf | 2nd&8 | Jac8 | Penalty: Delay of Game on Buffalo (Ryan Fitzpatrick) -5 yards. | | |
| Buf | 2nd&13 | Jac13 | Ryan Fitzpatrick pass to the left to Stevie Johnson for 13 yards for a TOUCHDOWN. | | |
| Buf | | | Rian Lindell extra point is good. | | |
| Buf | | | Drive Stats: 8 plays, 61 yards, 3min 54sec | 10 | 24 |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | | | Rian Lindell kicks off to the Jac6. Quan Cosby return for 21 yards to Jac27. Tackled by Ruvell Martin and Marcus Easley. | | |
| Jac | 1st&10 | Jac27 | Montell Owens rush to the left for 3 yards to the Jac30. Tackled by Nick Barnett and Kyle Moore. | | |
| Jac | 2nd&7 | Jac30 | Chad Henne pass to the right to Cecil Shorts for 7 yards to the Jac37. Tackled by Bryan Scott. | | |
| Jac | 1st&10 | Jac37 | Chad Henne incomplete pass to the middle intended for Marcedes Lewis defensed by Justin Rogers. | | |
| Jac | 2nd&10 | Jac37 | Chad Henne pass to the right to Justin Blackmon for 9 yards to the Jac46. Tackled by Stephon Gilmore. | | |
| Jac | 3rd&1 | Jac46 | Chad Henne rush for no gain to the Jac46. | | |
| Jac | 3rd&- | Jac46 | Penalty: Offside on Buffalo (Spencer Johnson) 5 yards. | | |
| Jac | 1st&10 | Buf49 | Penalty: Illegal Contact on Buffalo (Ron Brooks) 5 yards. | | |
| Jac | 1st&10 | Buf44 | Montell Owens rush to the left for 7 yards to the Buf37. Tackled by Stephon Gilmore. | | |
| Jac | 2nd&3 | Buf37 | Chad Henne sacked at Buf39 for a loss of 2 yards by Kyle Moore. | | |
| Jac | 3rd&5 | Buf39 | Chad Henne incomplete pass to the left intended for Cecil Shorts. | | |
| Jac | 4th&5 | Buf39 | Chad Henne incomplete pass to the left intended for Marcedes Lewis. | | |
| Buf | 1st&10 | Buf39 | Fred Jackson rush to the right for 4 yards to the Buf43. Tackled by Chris Prosinski and Jason Babin. | | |
| Buf | 2nd&6 | Buf43 | Fred Jackson rush to the left for 9 yards to the Jac48. Tackled by Russell Allen and Paul Posluszny. | | |
| Buf | 1st&10 | Jac48 | Fred Jackson rush to the left for 5 yards to the Jac43. Tackled by Russell Allen and Mike Harris. | | |
| Buf | 2nd&5 | Jac43 | Fred Jackson rush up the middle for 6 yards to the Jac37. Tackled by C.J. Mosley and George Selvie. | | |
| Buf | 1st&10 | Jac37 | Fred Jackson rush to the right for 3 yards to the Jac34. Tackled by Dawan Landry. | | |
| Buf | 2nd&7 | Jac34 | Fred Jackson rush to the right for 3 yards to the Jac31. Tackled by Kevin Rutland and Dawan Landry. | | |
| Buf | 3rd&4 | Jac31 | Ryan Fitzpatrick pass to the left to Fred Jackson for a loss of 1 yard to the Jac32. Tackled by Paul Posluszny. | | |
| Buf | 4th&5 | Jac32 | Rian Lindell 50 yard field goal attempt is GOOD. Holder: Shawn Powell. | | |
| Buf | | | Drive Stats: 8 plays, 29 yards, 4min 52sec | 10 | 27 |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | | | Rian Lindell kicks off to the Jac0. Touchback. | | |
| Jac | 1st&10 | Jac20 | Chad Henne incomplete pass to the left intended for Marcedes Lewis. | | |
| Jac | 2nd&10 | Jac20 | Chad Henne pass to the left to Cecil Shorts for 9 yards to the Jac29. Tackled by Ron Brooks. | | |
| Jac | 3rd&1 | Jac29 | Montell Owens rush up the middle for a loss of 1 yard to the Jac28. Tackled by Da'Norris Searcy and Kyle Williams. | | |
| Jac | 4th&2 | Jac28 | Penalty: False Start on Jacksonville (Julian Stanford) -5 yards. | | |
| Jac | 4th&7 | Jac23 | Bryan Anger punts for 39 yards to Buf38. Justin Rogers - no return. Tackled by Antwon Blake. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | 1st&10 | Buf38 | C.J. Spiller rush to the right for a loss of 1 yard to the Buf37. Tackled by Russell Allen and George Selvie. | | |
| |
| Fourth Quarter |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | 2nd&11 | Buf37 | Ryan Fitzpatrick pass to the left to Brad Smith for 12 yards to the Buf49. Tackled by Mike Harris. | | |
| Buf | 1st&10 | Buf49 | Fred Jackson rush to the left for 7 yards to the Jac44. Tackled by Dawan Landry. | | |
| Buf | 2nd&3 | Jac44 | C.J. Spiller rush to the left for 44 yards for a TOUCHDOWN. | | |
| Buf | | | Rian Lindell extra point is good. | | |
| Buf | | | Drive Stats: 4 plays, 62 yards, 2min 7sec | 10 | 34 |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | | | Rian Lindell kicks off to the Jac1. Quan Cosby return for 16 yards to Jac17. Tackled by Corey McIntyre. | | |
| Jac | 1st&10 | Jac17 | Montell Owens rush to the left for 4 yards to the Jac21. Tackled by Jairus Byrd. | | |
| Jac | 2nd&6 | Jac21 | Penalty: Holding on Buffalo (Crezdon Butler) 5 yards. | | |
| Jac | 1st&10 | Jac26 | Chad Henne pass to the middle to Jordan Shipley for 6 yards to the Jac32. Tackled by Ron Brooks. | | |
| Jac | 2nd&4 | Jac32 | Chad Henne pass to the right to Jordan Shipley for 8 yards to the Jac40. Tackled by Ron Brooks. | | |
| Jac | 1st&10 | Jac40 | Chad Henne pass to the middle to Chad Henne for a loss of 6 yards to the Jac34. Tackled by Shawne Merriman and Alex Carrington. | | |
| Jac | 2nd&16 | Jac34 | Chad Henne incomplete pass to the right intended for Jordan Shipley. | | |
| Jac | 3rd&16 | Jac34 | Chad Henne pass to the middle to Cecil Shorts for 9 yards to the Jac43. Tackled by George Wilson. | | |
| Jac | 4th&7 | Jac43 | Bryan Anger punts for 52 yards to Buf5. Justin Rogers - no return. FUMBLE, recovered by Jac (Antwon Blake). | | |
| Jac | 1st&5 | Buf5 | Chad Henne pass to the right to Cecil Shorts for 5 yards for a TOUCHDOWN. | | |
| Jac | | | Montell Owens 2 pt rush attempt. Successful. | | |
| Jac | | | Drive Stats: 1 plays, 5 yards, 4sec | 18 | 34 |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | | | Josh Scobee kicks off to the Buf0. Touchback. | | |
| Buf | 1st&10 | Buf20 | Fred Jackson rush up the middle for 4 yards to the Buf24. Tackled by C.J. Mosley. | | |
| Buf | 2nd&6 | Buf24 | Fred Jackson rush up the middle for 3 yards to the Buf27. Tackled by C.J. Mosley and Terrance Knighton. | | |
| Buf | 3rd&3 | Buf27 | Buffalo Bills timeout. | | |
| Buf | 3rd&3 | Buf27 | C.J. Spiller rush to the left for 1 yard to the Buf28. Tackled by Russell Allen. | | |
| Buf | 4th&2 | Buf28 | Shawn Powell punts for 46 yards to Jac26. No return. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | 1st&10 | Jac26 | Chad Henne incomplete pass to the left intended for Cecil Shorts. | | |
| Jac | 2nd&10 | Jac26 | Chad Henne pass to the right to Cecil Shorts for 5 yards to the Jac31. Tackled by Ron Brooks. Penalty: Unnecessary Roughness on Buffalo (Ron Brooks) 15 yards. | | |
| Jac | 1st&10 | Jac46 | Chad Henne incomplete pass to the left intended for Jordan Shipley. | | |
| Jac | 2nd&10 | Jac46 | Chad Henne pass to the left to Kevin Elliott for 13 yards to the Buf41. Tackled by Ron Brooks. | | |
| Jac | 1st&10 | Buf41 | Chad Henne incomplete pass to the right intended for Justin Blackmon defensed by Stephon Gilmore. | | |
| Jac | 2nd&10 | Buf41 | Penalty: Holding on Jacksonville (Eugene Monroe) -10 yards. | | |
| Jac | 2nd&20 | Jac49 | Jacksonville Jaguars timeout. | | |
| Jac | 2nd&20 | Jac49 | Chad Henne rush to the left for 1 yard to the Jac50. Tackled by Ron Brooks. | | |
| Jac | 3rd&19 | Jac50 | Chad Henne pass to the right to Montell Owens for 11 yards to the Buf39. Tackled by Justin Rogers. | | |
| Jac | 4th&8 | Buf39 | Chad Henne incomplete pass to the left intended for Justin Blackmon. | | |
| Buf | 1st&10 | Buf39 | Fred Jackson rush to the left for 14 yards to the Jac47. Tackled by Kevin Rutland. | | |
| Buf | 1st&10 | Jac47 | Fred Jackson rush to the right for 2 yards to the Jac45. Tackled by Paul Posluszny and Terrance Knighton. | | |
| Buf | 2nd&8 | Jac45 | Fred Jackson rush to the right for a loss of 2 yards to the Jac47. Tackled by Terrance Knighton. | | |
| Buf | 3rd&10 | Jac47 | Fred Jackson rush to the left for 5 yards to the Jac42. Tackled by Dawan Landry. | | |
| Buf | 4th&5 | Jac42 | Shawn Powell punts for 27 yards to Jac15. No return. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | 1st&10 | Jac15 | Chad Henne pass to the right to Kevin Elliott for 11 yards to the Jac26. Tackled by Ron Brooks. | | |
| Jac | 1st&10 | Jac26 | Penalty: Pass Interference on Buffalo (Stephon Gilmore) 26 yards. | | |
| Jac | 1st&10 | Buf48 | Chad Henne sacked at Jac44 for a loss of 8 yards by Alex Carrington. | | |
| Jac | 2nd&18 | Jac44 | Chad Henne pass to the right to Marcedes Lewis for 24 yards to the Buf32. Tackled by Nick Barnett and Da'Norris Searcy. | | |
| Jac | 1st&10 | Buf32 | Chad Henne incomplete pass to the left intended for Kevin Elliott defensed by Ron Brooks. | | |
| Jac | 2nd&10 | Buf32 | Chad Henne pass to the left to Jordan Shipley for 5 yards to the Buf27. | | |
| Jac | 3rd&5 | Buf27 | Two Minute Warning. | | |
| Jac | 3rd&5 | Buf27 | Chad Henne incomplete pass to the left intended for Kevin Elliott defensed by Ron Brooks. | | |
| Jac | 4th&5 | Buf27 | Chad Henne incomplete pass to the middle intended for Jordan Shipley defensed by Alex Carrington. | | |
| Buf | 1st&10 | Buf27 | Fred Jackson rush up the middle for 2 yards to the Buf29. Tackled by Julian Stanford and Jeremy Mincey. | | |
| Buf | 2nd&8 | Buf29 | Jacksonville Jaguars timeout. | | |
| Buf | 2nd&8 | Buf29 | Fred Jackson rush to the left for 2 yards to the Buf31. Tackled by Mike Harris. | | |
| Buf | 3rd&6 | Buf31 | Jacksonville Jaguars timeout. | | |
| Buf | 3rd&6 | Buf31 | Fred Jackson rush up the middle for 4 yards to the Buf35. Tackled by Jeremy Mincey and Paul Posluszny. | | |
| Buf | 4th&2 | Buf35 | Buffalo Bills timeout. | | |
| Buf | 4th&2 | Buf35 | Shawn Powell punts for 44 yards to Jac21. Quan Cosby return for 15 yards to Jac36. Tackled by Corey McIntyre. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Jac | 1st&10 | Jac36 | Chad Henne pass intended for Kevin Elliott INTERCEPTED by Jairus Byrd and returned for 45 yards. Tackled by Eugene Monroe. | | |
| Team | Down | Spot | Play | Jac | Buf |
| Buf | 1st&9 | Jac9 | Ryan Fitzpatrick rush up the middle for a loss of 1 yard to the Jac10. | | |