Depth Chart
| Position | Starter | 2nd | 3rd | 4th | 5th | 6th |
| Catcher | Jason Castro | Chris Gimenez | ||||
| First Base | Joe Mauer | |||||
| Second Base | Brian Dozier | |||||
| Shortstop | Jorge Polanco | Eduardo Escobar | ||||
| Third Base | Miguel Sanó | |||||
| Left Field | Eddie Rosario | |||||
| Center Field | Byron Buxton | |||||
| Right Field | Max Kepler | |||||
| Designated Hitter | Robbie Grossman | |||||
| Starting Pitcher | Ervin Santana | Kyle Gibson | José Berríos | Adalberto Mejía | Nik Turley | |
| Closer | Brandon Kintzler | |||||
| Relief Pitcher | Taylor Rogers | Matt Belisle | Craig Breslow | Tyler Duffey | Buddy Boshers | Alan Busenitz |
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