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| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jerzy Janowicz | Loss | 4-6, 6-7 (5-7) |
| Mutua Madrid Open | ||
| Surface: Clay | Date: May 4 - May 12 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Robin Haase | Win | 7-6 (7-5), 7-6 (7-2) |
| Third Round | Fernando Verdasco | Win | 4-6, 6-3, 6-2 |
| Quarterfinals | Stanislas Wawrinka | Loss | 2-6, 7-6 (11-9), 4-6 |
| Tennis Masters Monte-Carlo | ||
| Surface: Clay | Date: Apr. 14 - Apr. 21 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Nikolay Davydenko | Win | 7-6 (7-3), 6-2 |
| Third Round | Jurgen Melzer | Win | 6-3, 6-0 |
| Quarterfinals | Stanislas Wawrinka | Win | 2-6, 6-3, 6-4 |
| Semifinals | Rafael Nadal | Loss | 3-6, 6-7 (3-7) |
| Miami Masters | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Viktor Troicki | Win | 7-6 (8-6), 6-3 |
| Third Round | Jarkko Nieminen | Win | 6-3, 6-3 |
| Fourth Round | Marin Cilic | Loss | 5-7, 6-7 (4-7) |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | James Blake | Win | 7-6 (8-6), 6-4 |
| Third Round | Mardy Fish | Win | 7-6 (7-4), 7-6 (7-0) |
| Fourth Round | Milos Raonic | Win | 4-6, 7-5, 6-4 |
| Quarterfinals | Novak Djokovic | Loss | 3-6, 1-6 |
| Dubai Tennis Championships | ||
| Surface: Hard | Date: Feb. 25 - Mar. 2 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Michael Llodra | Loss | 6-7 (3-7), 2-6 |
| Open 13 | ||
| Surface: Hard | Date: Feb. 18 - Feb. 24 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Nikolay Davydenko | Win | 7-6 (7-1), 6-3 |
| Quarterfinals | Bernard Tomic | Win | 4-6, 6-3, 7-6 (12-10) |
| Semifinals | Gilles Simon | Win | 6-2, 6-2 |
| Final | Tomas Berdych | Win | 3-6, 7-6 (8-6), 6-4 |
| ABN AMRO World Tennis Tournament | ||
| Surface: Hard | Date: Feb. 11 - Feb. 17 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Igor Sijsling | Loss | 6-7 (3-7), 6-4, 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 13 - Jan. 27 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Michael Llodra | Win | 6-4, 7-5, 6-2 |
| Second Round | Go Soeda | Win | 6-3, 7-6 (7-1), 6-3 |
| Third Round | Blaz Kavcic | Win | 6-2, 6-1, 6-4 |
| Fourth Round | Richard Gasquet | Win | 6-4, 3-6, 6-3, 6-2 |
| Quarterfinals | Roger Federer | Loss | 6-7 (4-7), 6-4, 6-7 (4-7), 6-3, 3-6 |
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